Presentation topic
Structure-based design of new therapeutics for leukemia
Research Focus
I am a professor of Pathology and co-leader of the Developmental Therapeutics program at the University of Michigan. My research is focused on development of new therapies for leukemia, and my laboratory developed first-in-class menin inhibitors, including Ziftomenib (co-developed with Kura Oncology) that is in phase II clinical trials in AML patients. My lab. uses interdisciplinary approaches, including medicinal chemistry, structure-based design, biochemistry, and biological studies to develop new therapeutics.
